The state of Connecticut currently has 28 active clinical trials seeking participants for Pain research studies. These trials are conducted in various cities, including New Haven, Hartford, Farmington and Stamford.
A Study of Retatrutide (LY3437943) in Participants Who Have Obesity or Overweight
Recruiting
The purpose of this study is to evaluate the efficacy and safety of retatrutide in participants who have obesity or overweight (J1I-MC-GZBJ master protocol) including subsets of participants who have knee osteoarthritis (OA) (J1I-MC-GOA1) or who have obstructive sleep apnea (OSA) (J1I-MC-GSA1). This study will last about 89 weeks and will include up to 24 visits.
Gender:
All
Ages:
18 years and above
Trial Updated:
06/17/2024
Locations: Yale University School of Medicine, New Haven, Connecticut +1 locations
Conditions: Obesity, Overweight, Knee Pain Chronic, Knee Osteoarthritis, Obstructive Sleep Apnea
Pain and Weight Treatment: Development and Trial of PAW
Recruiting
Pediatric weight management efficacy is impacted by failure to complete treatment protocols and, for those that do complete treatment, a return to unhealthy behaviors. This project tests whether treating pain, a common comorbid condition to pediatric obesity, will enhance treatment. This study will generate results that can be translated into immediate improvements in care for families seeking treatment for pediatric obesity.
Gender:
All
Ages:
Between 12 years and 18 years
Trial Updated:
06/12/2024
Locations: Connecticut Children's Medical Center, Hartford, Connecticut
Conditions: Obesity, Adolescent, Pain, Chronic, CBT
Radiofrequency (RF) Ablation Prospective Outcomes Study
Recruiting
The objective of this study is to compile real-world outcomes of Boston Scientific commercially approved radiofrequency (RF) ablation systems in the treatment of patients diagnosed with pain and in use for central nervous system (CNS) applications for other disorders.
Gender:
All
Ages:
0 years and above
Trial Updated:
06/11/2024
Locations: The Spine Wellness Center in Westport, Westport, Connecticut
Conditions: Pain, Chronic
Patient Retrospective Outcomes (PRO)
Recruiting
This study will evaluate de-identified (anonymous) data in subject medical charts to review the clinical outcomes of various treatment approaches in the treatment of chronic pain.
Gender:
All
Ages:
18 years and above
Trial Updated:
06/11/2024
Locations: Advanced Diagnostic Pain Treatment Centers, New Haven, Connecticut
Conditions: Chronic Pain
A Master Protocol Study (LY900028) of Multiple Intervention-Specific-Appendices (ISAs) in Participants With Chronic Pain
Recruiting
The purpose of the chronic pain master protocol is to compare independent pain interventions and establish an overarching structure for the disease-state addenda (DSA) and intervention-specific appendices (ISAs). The ISAs may start independently of other ISAs as interventions become available for clinical testing.
Gender:
All
Ages:
18 years and above
Trial Updated:
05/24/2024
Locations: CMR of Greater New Haven, LLC, Hamden, Connecticut
Conditions: Osteoarthritis, Knee, Diabetic Neuropathic Pain, Chronic Low-back Pain
Stepped Care for Patients to Optimize Whole Recovery
Recruiting
This is a prospective, randomized clinical trial of 316 patients with opioid use disorder (OUD) and chronic pain (CP) to test the effectiveness of treatment as usual compared with Stepped Care for Patients to Optimize Whole Recovery (SC-POWR) to reduce illicit opioid use and pain interference (Aim 1) and decrease alcohol use, anxiety, depression, and stress, and improve sleep (Aim 2). Eligible participants will begin medications for opioid use disorder (MOUD) and will be randomized to receive SC... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
05/14/2024
Locations: APT Foundation, New Haven, Connecticut +1 locations
Conditions: Opioid Use Disorder, Chronic Pain
Piloting a Novel Peer Support Pain Self-Management Intervention (Project CONNECT)
Recruiting
The proposed study will test the feasibility and acceptability of an 8-week home-based reciprocal peer support pain self-management intervention (CONNECT) for women Veterans with chronic musculoskeletal pain. The use of this format will improve the accessibility of treatment to women Veterans who experience logistical, healthcare delivery and psychosocial barriers to care. To address these barriers women Veterans who enroll in CONNECT will be paired and work together to learn/practice pain copin... Read More
Gender:
Female
Ages:
18 years and above
Trial Updated:
04/30/2024
Locations: VA Connecticut Healthcare System West Haven Campus, West Haven, CT, West Haven, Connecticut
Conditions: Musculoskeletal Pain
Computer Based Treatment for Cognitive Behavioral Therapy and Cooperative Pain Education and Self-Management
Recruiting
The investigators plan to develop and pilot test an integrated, web-based cognitive behavioral approach and then conduct a randomized clinical trial evaluating its efficacy relative to standard care in a large and diverse sample of individuals with chronic pain treated with buprenorphine or methadone. The new program will retain key components of Dr. Carroll's computer-based training for cognitive-behavioral therapy (CBT4CBT), including its emphasis on teaching cognitive and behavioral coping sk... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
04/05/2024
Locations: Liberation Programs, Bridgeport, Connecticut +2 locations
Conditions: Opioid Use Disorder, Chronic Pain
Pilot of Peers Enhancing Engagement for Pain Services
Recruiting
Chronic non-cancer pain is common among Veterans, and more work is needed to understand how best to support Veterans with chronic pain to improve pain-related function and quality of life. Peer specialists may be valuable resource to support Veterans in pain management. Peer specialists, individuals with lived experience who are hired and trained to work with Veterans, are increasingly being used outside traditional mental health settings. More research is needed to understand how best to train... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
04/03/2024
Locations: VA Connecticut Healthcare System West Haven Campus, West Haven, CT, West Haven, Connecticut
Conditions: Chronic Pain
Cannabidiol in Opioid Use Disorder and Chronic Pain
Recruiting
This is a double-blind, randomized, placebo-controlled cross-over human laboratory study with a duration of approximately 3 weeks, during which participants will come to the testing site for a total of five times: one initial screening session, and four experimental sessions where study medication, Cannabidiol (CBD) will be administered, separated by at least 72 hours to limit carryover effects.
Gender:
All
Ages:
Between 18 years and 70 years
Trial Updated:
03/05/2024
Locations: Department of Veterans Affairs Hospital, West Haven, Connecticut
Conditions: Chronic Pain
Validation of the Cervicothoracic Differentiation Test
Recruiting
The goal of this clinical trial is to compare the effects of two spinal manipulations in adults between the ages of 18-65 based on the results of a non-invasive clinical test. The main question it aims to answer is: • Does matched or unmatched region of manipulation based on the CTDT result in greater reduction of pain levels and improvement in range of motion in adults with neck pain compared to unmatched manipulations? Participants will be asked to: rate their pain with neck movement, complet... Read More
Gender:
All
Ages:
Between 18 years and 65 years
Trial Updated:
02/28/2024
Locations: University of Hartford, West Hartford, Connecticut
Conditions: Neck Pain
The DISCOVER INOCA Prospective Multi-center Registry
Recruiting
The overall objective of this multi-center registry is to identify specific phenotypes of INOCA with both an anatomic evaluation (coronary angiography and intravascular imaging) and physiologic assessment with the Abbott Coroventis Coroflow Cardiovascular System, and to determine long-term outcomes.
Gender:
All
Ages:
18 years and above
Trial Updated:
02/14/2024
Locations: Yale University, New Haven, Connecticut
Conditions: Ischemia and no Obstructive Coronary Artery Disease, Coronary Microvascular Dysfunction, Coronary Vasospasm, Endothelial Dysfunction, Microvascular Angina, Chest Pain With Normal Coronary Angiography